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Aleksandra Smirnova

North-Western State Medical University named after I.I. Mechnikov, Russian Federation

Title: Predicting the course of localized periodontitis of traumatic etiology after complex treatment

Abstract

 Due to the noteworthy prevalence of inflammatory periodontal diseases among the population, the problem of providing timely and quality care to prevent severe complications leading to tooth loss becomes urgent.  Predicting the outcome of the disease is a critical task. Examination and treatment of patients with localized periodontitis of traumatic etiology (LPT) were performed. We employed clinical, radiological, and functional methods of examining periodontal condition, and investigated laboratory blood parameters (complete blood count, C-reactive protein). Risk factors for the occurrence of LPT were assessed. Predicting the course of LPT based on changes in clinical and radiological indicators was accomplished by assessing treatment outcomes and calculating a prognostic score. Patients exhibited a noteworthy prevalence of somatic pathology, with cardiovascular diseases (RR=2.32), anemia (RR=2.26), and gastrointestinal tract disorders (RR=1.88) emerging as predominant conditions (p<0.001). With a concentration of C-reactive protein in the range of 3-10 mg/L, the risk of developing moderate-grade LPT increased 1.74-fold (RR=1.74; p=0.0022). The intense type of adaptive reaction of the body was detected in 30.4% and 50.7% of cases with mild and moderate grades of LPT, respectively, increasing the risk of a more severe grade by 1.8 times (p=0.0026).               

Pronounced local changes in the bone tissue of the alveolar process were observed 1.6-2 times more often in cases of moderate periodontitis vs. mild LPT (p=0.0035). Microcirculation in the inflammation zone decreased by 32% and 50.1% with mild and moderate grade of the disease, respectively (p<0.001).  The prognosis for the course of LPT was most significantly influenced by the concentration of C-reactive protein, the grade of LPT, the entropy of the leukocyte blood count, changes in the alveolar bone of the jaw, the duration of the disease, the history of previous periodontal treatment, and tooth splinting.  

Biography

Aleksandra Smirnova has completed his PHD at the age of 46 years from North-Western State Medical University, Russia. She is the Assistant of the Department of General Practice Dentistry at North-Western State Medical University named after I.I. Mechnikov, Russia. She has over 30 publication that have been cited over 80 times, and her publication h-index is 6. She has been serving as a reviewer and supervisor of students and clinical residents of North-Western State Medical University. Also she is a Secretary of the Accreditation Commission and Member of the State Final Certification of medical students.